Objective: Coronavirus disease (COVID-19) pandemic has spread globally. Malaysia is not spared from the impact of this health catastrophe; and has its own share of morbidity and mortality from the disease with the world population. As of 15th December 2020, Malaysia has recorded 86,618 cases of COVID-19 and had up to 422 deaths. Frontline healthcare workers (HCWs) faced a substantially higher risk of infection due to risk of COVID-19 exposure. In addition to that, juggling work and motherhood responsibilities is always a challenge for women healthcare workers. This case series illustrates some factors that contribute to the psychological distress of women HCWs during the pandemic.